POSTnATAL STEM CELLS
Postnatal stem cells are harvested from donated birth material collected from healthy live births. This is not to be confused with embryonic stem cells. Postnatal stem cells can be harvested from the umbilical cord tissue, umbilical cord blood, amniotic fluid, and amniotic tissue. Postnatal birth material contains young MSCs and HSCs and a host of other regenerative components. Because these cells are primitive and have not fully developed the surface proteins found on the outer membranes of older cells they are considered immune privileged with no blood type matching required. Since stem cells are greatly affected by the age and health of the patient, postnatal stem cells are especially appealing due to their potency and age. It is worth noting that there are variances in manufacturing protocols and donor sourcing that can greatly affect the final product. At BioWellness Group we only partner with top quality manufacturers. For further product specific information on the postnatal therapeutics we offer click here.
Bone Marrow Aspiration and Concentrate - BMAC
Bone marrow concentration and transplantation is a method for obtaining concentrated HSCs, which can be transplanted back to the patient in other locations (such as joints), or donated to an unrelated person. It requires special training to harvest and it can be painful with patient down time. The procedure is done under anesthesia with 2-3 hrs processing time and pain for a few days post-procedure. Transplants between unrelated patients require blood type matching to prevent graft vs host reaction. There is some concern regarding depleting the patient’s stem cell reserve.
Adipose Stromal Vascular Fraction -SVF
This technique involves harvesting MSCs from the patient’s own fat. A mini liposuction procedure is performed. MSCs are then isolated from adipose tissue. There are some concerns with the processing used to isolate the MSC’s from the tissue. Their safety in use for clinical applications is contested due to the risk of adipose MSCs to promote tumor cells to proliferate, differentiate, or metastasize or possibly even induce the growth of new tumors. Treatment is invasive with patient down time and older stem cells are subject to DNA damage.